RAF Typhoon FGR4s have operated alongside French warplanes in a combined operation targeting an subterranean weapons facility in Syria used by the Daesh militant organization, according to the British defence ministry.
The location, located using intelligence, was believed to be storing arms and explosives, the announcement noted, and was positioned in mountains just north of the historic site of Palmyra in the heart of Syria.
"Our aircraft used Paveway IV guided bombs to strike a several access tunnels down to the site... early reports indicate the strike was effective," officials stated.
There was no sign of any civilian impact in the operation on Saturday evening and every plane involved returned to base without incident, the ministry further stated.
The Typhoon FGR4s were assisted by a Voyager tanker plane.
Daesh - alternatively referred to as ISIS - established extremist governance over large swathes of Iraq and Syria until 2019.
"This operation underscores the UK's leading role, and resolve to operate in unison with allied nations, to stamp out any re-emergence of the terrorist group and their violent and radical beliefs in the area," Britain's Defence Chief the minister said.
RAF aircraft have conducted overwatch operations over Syrian airspace to "forestall any attempted comeback" of Islamic State after its routing at the climactic battle in Baghuz in the year 2019, the ministry said.
"I extend gratitude to all the members of British forces participating in this strike for their professionalism and their bravery," the Defence Secretary said. "They were among numerous British personnel stationed over Christmas and New Year. This action, to remove terrorist threats who endanger our safety, demonstrates how UK forces are always on standby, throughout the year, keeping Britain secure at home and influential overseas."
Last December, the American forces conducted what it termed a "major assault" targeting Daesh sites in the country, after an attack resulted in the deaths of two US servicemembers and a local interpreter in the Palmyra area.
The U.N. reports Islamic State still boasts an estimated 5,000 to 7,000 fighters in both countries.